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Folate and vitamin B12 status and their relation to hematological indices in healthy adults of Iranians: azar cohort study

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Oxidative stress In recent years, studies have shown that oxidative stress and nitrosative stress play vital roles in cisplatin-induced nephrotoxicity, which is characterized by increased malondialdehyde (MDA), 4-hydroxy, 8-hydroxydeoxyguanosine, and 3-nitrotyrosine, and decreased superoxide dismutase (SOD) and catalase (CAT) after cisplatin treatment

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However, very high doses aren't more effective than moderate doses for most people