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The authors of the same publication suggest this could be attributed to increased food intake and improved nutrient digestibility

(77) observed that the non-classical effector proteins Caspase-4/-5/-11 could regulate the tetrapeptide sequence identity of IL-1 and IL-18, thereby modulating IL-1 and IL-18 recruitment and activation, which provides a basis for the development of new therapies for related diseases

Specifically, it demonstrated profound increases in Superoxide Dismutase (SOD) and Glutathione Peroxidase

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Diagnosis typically involves blood tests (liver function tests, lipid profile, HbA1c), ultrasound imaging, and assessment for alternative or coexisting causes of liver disease, including alcohol intake, viral hepatitis B and C, autoimmune liver disease, haemochromatosis, and medication-induced liver injury