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The accumulation of amphetamines effectively reverses the transporter carrier mechanisms, leading to a massive, non-exocytotic efflux of vesicular dopamine out into the cytosol, where it is subsequently transported into the synaptic cleft (Wimalasena 2011)(see Figure 2 Mechanism B)

Calverley et al

[PubMed: 4742541] 318

Measurement and registration of change in OD was performed automatically using a broadband filter at a wavelength of 420580 nm

A GFD prevents these phenomena by curtailing shared sequences and cross-reactivity

While these findings provide important insights, we acknowledge that the exclusive use of mouse models of TNBC in our studies limits the clinical applicability of our findings