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Patient-derived resistant primary cells treated with miR-634 exhibited reduced viability upon treatment with 15 M and 30 M cisplatin, and concurrently enhanced sensitivity to carboplatin and doxorubicin, suggesting that the miR-634 delivery system could serve as a combination therapy strategy to reverse multidrug resistance [61]

Pregnancy and lactation safety has not been systematically studied, and as with most cosmetic and research compounds lacking definitive pregnancy safety data, conservative practice typically suggests avoiding use during pregnancy unless clearly needed, though the natural occurrence of GHK-Cu in the body and minimal systemic absorption from topical use suggest risk is likely to be low

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Also, IV doses used for skin lightening are even more unknown because they reach high blood levels fast

If your B12 is low and you also have hair shedding, heres a practical roadmap to get you on the road to recovery: The first step is to make sure you are getting enough vitamin b12 in your daily diet

PubMed DOI Sikiric P, Rucman R, Turkovic B, et al