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10.1016/j.freeradbiomed.2013.07.036 219 LynchE.SemradT.BelsitoV

These two drugs were not only able to enrich GSH contents and GPX activity and defend the heart against oxidative stress but also prevented DOX or I/R-induced myocardial injury [214,215,216,217]

FIGURE 1 The chemical structure of vitamin E includes a chromanol ring with one hydroxyl group and three, two or one methyl group on the aromatic ring

Some studies suggest that glutathione may inhibit melanogenesis by interfering with the activity of tyrosinase, an enzyme critical for melanin synthesis, which has led to its use in skin-lightening protocols