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Small-molecule drugs are the other type of targeted therapy that can penetrate cell surfaces to reach intracellular targets and slow growth or induce cell death [151]

Building on these genetic insights, Lian et al (199) successfully developed a clinical diagnostic model based on ferroptosis-related hub genes, specifically DECR1, GJA1, EFN2L2, PSAT1, SLC7A11, SOX2 and YAP1

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Maintaining structural and catalytic stability As a stabilizing carrier for nanozymes, hydrogels rely on network structural design and intermolecular interaction regulation to maintain nanozyme structural integrity and sustained catalytic activity [69]