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Clinicopathologic correlation of up-regulated genes identified using cDNA microarray and real-time reverse transcription-PCR in human colorectal cancer

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Antonarakis SE, Lyle R, Dermitzakis ET, Reymond A, Deutsch S (2004) Chromosome 21 and down syndrome: from genomics to pathophysiology

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Most children have not been exposed to the environmental factors long enough for these tumors to form which is likely to be the reason these are rare under 20 years of age, but as with most rare conditions, significant assessment of epidemiologic factors is difficult simply due to low numbers of cases