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Week 24 data for all participants, including non-cirrhotic and compensated cirrhotic (approx

doi: 10.1371/journal.pone.0013545 85 ShearnCTSmathersRLStewartBJFritzKSGalliganJJHailNJr.et al

herbal medicine is a widely available, safe, and nontoxic alternative [21,22,23,24,25,26,27,28,29]

Int 7 , 539547 (2013)

doi: 10.1210/clinem/dgab153 11

In contrast, intraocular and retinal IL-6 signaling has been implicated in BRB disruption, vascular leakage, and inflammatory activation, particularly via IL-6 trans-signaling pathways that impair endothelial barrier integrity (71, 223, 224)