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Additionally, the same group demonstrated that a glycolytic gene signature characterized CAR T cells obtained from patients with partial or no response to therapy

Mitochondrial dysfunction confers resistance to multiple drugs in Caenorhabditis elegans

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Accordingly, neurodegenerative changes are present in other areas of the nervous system, such as the peripheral, autonomic, and enteric nervous systems [15, 16], and -synuclein aggregates may be detected outside the nervous system, including in the digestive tract, skeletal muscles, heart, adrenal glands, kidneys, urogenital system, and skin [22]

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