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Preclinical studies in animal models, such as EAE and DSS-induced colitis, have consistently demonstrated the efficacy of targeting metabolic nodes like mTOR, AMPK, HIF-1, and PKM2 in rebalancing Th17/Treg responses

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doi: 10.1371/journal.pone.0198881 52 Costa-BauzACalvPHernndezYGrasesF

Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy

Two mechanisms have been identified to remove Hb and heme

Bisdemethoxycurcumin suppresses the progression of atherosclerosis and VSMC-derived foam cell formation by promoting lipophagy