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Any short-term improvement is often linked to the placebo effect or improved hydration rather than a true physiological change

Another common use for methyl B12 is in children with autism spectrum disorders and dyslexia and often involves injecting methyl-B12 into subcutaneous fat, allowing for slow and sustained release from the tissue

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Someone training with poor form, low volume, and eating 0.5g protein per lb will see minimal DES results

However, it is a surgical procedure with associated risks and a longer recovery time