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Once preliminary evidence suggests one therapy is better, randomization may be considered unethical

Kusumi M, Ishizaki K, Kowa H, Adachi Y, Takeshima T, Sakai F, Nakashima K (2003) Glutathione S-transferase polymorphisms: susceptibility to migraine without aura

Babcock M, de Silva D, Oaks R, Davis-Kaplan S, Jiralerspong S, Montermini L, Pandolfo M, Kaplan J: Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin

In addition, the committee reviewed an extensive collection of material, primarily from the published, peer-reviewed scientific and medical literature

& Browse, J

doi: 10.1038/s41598-024-51369-0 78 KimD.AlptekinB.BudakH