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the cytoplasmic inhibitor KEAP1 and the transcriptional repressor BACH1, together with the different drug modalities serving as NRF2-activators

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For competition periods, scheduling an infusion 24 to 48 hours before a major event and again within 12 to 24 hours after strenuous exercise helps replenish electrolytes, amino acids, and B vitamins when the body needs them most

The second enzyme of GSH synthesis, GSH synthase (GS) is also regulated in a coordinated manner as GCL subunits and its up-regulation can further enhance the capacity of the cell to synthesize GSH