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Third, CpG recognizes TLR9 on human B cells and plasmacytoid dendritic cells (pDCs), while TLR9 activation in T cells and monocytes/macrophages further drives cytokine and chemokine secretion (Xie et al., 2024

Additionally, while the MRS measurements werent balanced between the two groups at baseline, we controlled for the potential limitation by covariate analyses

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