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However, recent research has suggested that serotonin may play a smaller role in depression than previously thought

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[DOI] [PMC free article] [PubMed] [Google Scholar] Hozo 2005 Hozo SP, Djulbegovic B, Hozo I

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The main metabolite, [ 3 H]proline (M1), accounted for 4.96% (female) and 3.93% (male) of the bile samples (Figure 5C)