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doi: 10.1007/s13204-022-02638-9 314 ZhangW.LiuQ

A meta-analysis on Astragalus and its extracts in stage III-IV diabetic nephropathy revealed that Astragalus inhibited early macrophage-induced nitric oxide synthase activity triggered by lipopolysaccharide, reduced NO and TNF- production, and decreased apoptosis in renal tubular epithelial cells (Lai et al., 2013