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Statistical analysis was performed using Graphpad prism for windows

The impact of oxidative stress in male infertility

Li Piani L, Vigano P, Somigliana E

Why Chronic Inflammation Matters Chronic inflammation is now recognized as a central driver of nearly every chronic disease we fear most, including: Cardiovascular disease Diabetes and metabolic syndrome Autoimmune conditions Alzheimers and other neurodegenerative diseases Its also a major contributor to biological aging

Involvement of the endocannabinoid system in drug addiction

Specifically, curcumin has been shown to mediate the covalent modification of the active site cysteine (Cys) 496 and selenocysteine (Sec) 497 residues in TrxR, subsequently destroying TrxR reduction activity, a process that is irreversible and further leads to dramatic pro-oxidant effects, the induction of NOX activity, and the production of ROS [97]