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Detection and clearance of damaged lysosomes by the endo-lysosomal damage response and lysophagy

Second, the MCD model does not robustly activate de novo lipogenesis, and GADD45 may influence lipid accumulation via alternative pathways, such as fatty acid uptake or oxidation, which were not functionally explored

The pH was continuously monitored but not actively controlled

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Researchers use IGF-1 LR3 to study cellular growth, tissue regeneration, and metabolic signaling in controlled laboratory and preclinical models