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Rather, any apparent cellular selectivity is likely determined jointly by factors such as target protein expression, E3 ligase distribution, tumor microenvironment (TME) features, and delivery strategy

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Preparation and evaluation of inhalable dry powder containing glucosamine-conjugated gefitinib SLNs for lung cancer therapy

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The external expression lies in cutis laxa, no luster, and stain occurrence

(113) found that miR-21-5p controlled the AKT/mTOR signaling pathway through MELK in vivo , reducing iron apoptosis in hepatocellular carcinoma cells