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Both preclinical and clinical trials were included Results: From 380 records, 70 studies met the inclusion criteria

Its potential is in a real biological effect involving tissue repair, control of inflammation, development of blood vessels, as well as in a general positive safety profile observed in animal studies and off-label use

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Concentration matrices, temporal exposure strategies, mechanistic readouts, scaffold design, and long-term remodeling assessments are essential to move from speculative appeal toward validated research relevance

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It has traditionally been used to support occasional digestive spasms and settle the gut before sleep.3 Plantain leaf, often overlooked, is a quiet workhorse in the protocol