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Hu et al (42) showed that the expression level of GPX3 is positively associated with the IC50 of numerous drugs, including paclitaxel, 5-fluorouracil, carboplatin, etoposide, cisplatin and doxorubicin

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When ingested as a nutritional supplement preferably in the racemic mixture form, LA contains two isomers (1:1 of R-LA and S-LA), in which S-LA may prevent polymerization of R-LA and thus increases the bioavailability of the later (De Araujo et al., LA is found in both vegetable and animal-based foods, identified as lipoyl-lysine (coupling of LA to specific lysine residues

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