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The specific reactions mostly yield (R)--butyrolactone at enhanced enantiomeric purity, whereas (S)-3-hydroxybutyric acid esters, if at all, are obtained only in relatively low amounts (examples 1, 6, 7)

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and Oura Ring) has been shown to be consistent with clinical actigraphy measurements, but also overestimates sleep and underestimates wakefulness in bed compared with polysomnography