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Insulin is a naturally occurring endocrine hormone produced by pancreatic -cells that regulates blood glucose by facilitating its uptake into the liver, muscles, and adipose tissue, and supporting metabolic processes [2]

Modern pharmacology indicates its efficacy includes antitumor activity, enzyme-lowering activity, and anti-fibrotic activity [174]

Furthermore, dyslipidemia in pSS has been associated with several demographic factors, including gender, age, smoking status, and disease activity, with more pronounced lipid abnormalities observed in patients with heightened autoimmune responses and elevated inflammation levels [60]

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Moustafa AA, Chakravarthy S, Phillips JR, Gupta A, Keri S, Polner B, Frank MJ, Jahanshahi M (2016) Motor symptoms in Parkinsons disease: a unified framework

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