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Selective Induction of Apoptosis by HMG-CoA Reductase Inhibitors in Hepatoma Cells and Dependence on P53 Expression

The peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1) is a key regulatory factor in this biological mechanism [166]

From these data a Mg 2+ or Mn 2+ -dependent catalysis was concluded as also demonstrated for other members of the enzyme superfamily (Hurley et al., 1991

The absorption of ingested aluminum is very low, with the GI tract only absorbing 0.1% to 1.0% the rest is excreted