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In astrocytes, Mn-induced ER stress activates the PERK/eIF2 pathway and promotes a detrimental A1-reactive phenotype, linking ER stress to astrocyte-driven inflammation and Mn neurotoxicity 178

General procedure for the synthesis of final compounds 9a-9u Compounds 8a (1 equiv.) in 1,4-dioxane (10 volumes) at 0 C was added 4 M HCl in 1,4-dioxane (4 equiv.)

Oxford University Press, New York Sun Q, Sotayo A, Cazzulino AS et al (2017) Proximodistal heterogeneity of hippocampal CA3 pyramidal neuron intrinsic properties, connectivity, and reactivation during memory recall