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doi: 10.3233/JAD-160685 [DOI] [PMC free article] [PubMed] [Google Scholar] 227.Rachmian N, Medina S, Cherqui U, et al

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But they come with significant drawbacks: high cost, injection site reactions, increased infection risk due to immune suppression, and the development of anti-drug antibodies over time that can reduce efficacy