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To assess whether scTS2/16-stimulated growth caused shifts in the transcriptome of the cells, bulk sequence experiments were performed on control and Ab-stimulated 3D BME cultures of P26N colon, Duo-72 duodenum and J2 jejunum organoids (Extended Data Fig

Calcium Hydroxylapatite (CaHA) (brand name: Radiesse) and Poly-L-Lactic Acid (brand name: Sculptra) are solutions injected under the skin to stimulate collagen

Table 1 Primers used in various experiments

Considering that CD8 + T cells in pSS LGs, including CD103n CD8 + T and CD103p CD8 + T cells, had a high score in the Trm signature gene set, but the lowest score in Trm downregulated genes, we defined them as Trm cells (Figure 3A and Supplemental Figure 4A)