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Data from a double-blind RCT suggest short-term ALA supplementation can be beneficial for idiopathic pain without altering glycemia in patients with normal levels (45) , but another trial did not find it helpful for fibromyalgia (46)

In addition, a new phase-III clinical trial was started two years ago to evaluate the effects of enzastaurin in patients with diffuse large B-cell lymphoma

Am J Gastroenterol 2001;96:156370

Both of these carnitine metabolites are known as serum biomarkers of preeclampsia and have been shown to increase under hypoxic conditions in a cultured placental choriocarcinoma cell line (the BeWo line) 30

& Ronco, C