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doi: 10.1038/nrm2466

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In a micronucleus assay in mice, aspartame was administered as a single oral dose at 2501000 mg/kg bw by gavage, and bone marrow and peripheral blood samples were obtained at 24, 48, or 72 hours after dosing

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(Do not wait for assay results to begin acetylcysteine treatment.) 2

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It is widely known they both posses serine and threonine phosphorylation capability

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Samples were analyzed in triplicate using an Amplex Red kit (Amplex Red Hydrogen Peroxide/Peroxidase Assay Kit

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5 Conclusion and Perspectives Dysfunction of the tumor suppressor p53 has a widespread impact during carcinogenesis

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