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Univariate and multivariate analyses (Table 2) revealed that the serum level of pgRNA before HCC treatment ( p =0.001, HR [4.122, 1.7659.629]), maximum tumor diameter ( p =0.037, HR [1.095, 1.0061.192]), and total bilirubin ( p =0.024, HR [1.019, 1.0021.035]) were independent risk factors for recurrence

Authors of the latter study reported further increase of sperm density on subsequent visits, and 2 pregnancies within 3 months

(Table 1) The patient displayed a high-anion gap metabolic acidosis (HAGMA): serum anion gap (AG), corrected for hypoalbuminemia equalled 25.3, c AG = AG + 2.5 (4-albumine in g/dL)

Moreover glutaminolysis-mediated mTORC1 activation required prolyl hydroxylase (PHD) enzymatic activity in a HIF -independent manner [89]

10.3389/fimmu.2019.02750 475 WangZ.ZhangL.QinC

Kaufman 1994)