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Interestingly, people with pernicious anemia are more likely also to have other autoimmune disorders like type 1 diabetes, autoimmune thyroid disease, and a skin condition called vitiligo

Andrs E, Zulfiqar AA, Serraj K, et al

10.1038/s41398-022-02081-y 76 JamuarS

In the present study, the Res FM rat model exhibited hyperalgesic and allodynic behaviors

Therefore, KO treatments balance pro- and anti-inflammatory cytokines and modulate the inflammatory response induced by UVB radiation effects ( Clinical studies have shown that intake of n -3 PUFA can reduce the pro-inflammatory and immunosuppressive prostaglandin E2 (PGE2) production in human skin exposed to UV radiation, reduce erythema development, and protect the skin from immunosuppression

Later studies found similar patterns in Alzheimer's disease, Parkinson's disease, and COVID-19