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Several risk genes encode voltage-gated calcium and chloride channels known to modulate glutamate receptor activity (CACNA1C and CLCN3), metabotropic receptors (glutamate (GRM1) and GABA (GABBR2)), and the NMDA-R subunit (GRIN2A)

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The first three mechanisms are identical between the two formulations

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These findings further confirm that KU-57788-induced DRP1-dependent mitochondrial fission occurs independently of DNA-PKcs

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Neurology 49, 597606

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Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling

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