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While LifeWave points to clinical studies (see links to two examples in the References section if you want to check them out for yourselves) in support of their X39 patches, the studies I found on these patches in my opinion are not convincing as they were small, had questionable or unclear methods (e.g

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A hypoxia-modifying therapy intended to both reduce hypoxia and prevent tumor cell repopulation has been the subject of several preclinical and clinical studies (Kaanders 2002)

The preclinical literature does not prominently describe heart rate elevation

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More needs to be done A spokesperson for the TGA says it has been aware of tanning nasal sprays and other products containing melanotan for some time and in the past five years it has received several reports of alleged non-compliance with the TGA Act