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Indeed, HO-1 induction fosters the polarization of macrophages towards an anti-inflammatory M2-like profile and promotes a tolerogenic phenotype in DCs (83, 94), both reducing the activation of T cells and favoring the Treg differentiation, resulting in the suppression of autoreactive responses (47)

The similarity between overlap in the pathophysiology of ME/CFS and FM was demonstrated by Schutzer et al

London: Academic Press (2020)

PMID: 106 TyagiAMYuMDarbyTMVaccaroCLiJ-YOwensJAet al

Programming cells by multiplex genome engineering and accelerated evolution

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