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Oncogenic RNA-binding protein musashi2 (MSI2) physically binds BCAT1 transcript and positively regulates its expression to drive CML progression (Hattori et al., 2017)

Bead samples were immediately reduced with 10 mM TCEP (55 C for 1 h), alkylated with 18.75 mM iodoacetamide (room temperature for 30 min) and then digested from the beads with trypsin (2.5 g trypsin

The LPS group received an i.v

Ser1177 phosphorylation also increases the Ca 2+ sensitivity of the synthase, permitting CaM binding and enzyme activation at lower intracellular Ca 2+ levels (Tran et al., 2009

Several of these copperbinding motifs catalyze formation of reactive oxygen species (ROS), which is believed to be involved in these proteins role in neurodegenerative disorders

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