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GST activities in mock- and GSTP1 -transfected HepG2 cells were characterized by measuring CDNB conjugation to GSH in total cell lysates ( Table 1 )

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Upon activation, phosphorylated Nrf2 translocates to the nucleus, where it binds to AREs and promotes the expression of antioxidant proteins, including HO-1 and NQO1 (64, 65)