epithalon vs gdf11 Systemic attenuates depression-like phenotype in aged mice via stimulation of neuronal autophagy Rather than a “rejuvenating” agent,
Rather than a rejuvenating agent, GDF11 may have a detrimental effect on liver senescence. Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy [2021, open access] : r longevity Supraphysiologic Administration of GDF11 Induces Cachexia in Part by Upregulating GDF15: Cell Reports Frontiers The GDF11 Promotes Nerve Regeneration After Sciatic Nerve Injury in Adult Rats by Promoting Axon Growth and Inhibiting Neuronal Apoptosis GDF11 reverses mood and memory declines in aging Nature Aging GDF11 induces chemosensitization in human hepatocellular carcinoma cells by decreasing drug efflux transporters Multifaceted Benefits of GDF11 Treatment in Spinal Cord Injury: In Vitro and In Vivo Studies
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