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Description

In mammals, the biosynthesis of melatonin starts with the conversion of tryptophan to l-5-hydroxytryptophan, which is converted to serotonin [5-hydroxytryptamine(5-HT)] by the aromatic l-amino acid decarboxylase (AADC)

Gaps: dosing, delivery, safety, and large RCTs remain

As a neurologist deeply invested in the evolving landscape of medicine, I find the recent publication by Porcari and colleagues in Cell both timely and one day may be transformative