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In an OIS model induced by Nras G12v overexpression in hepatocytes of immunodeficient Nod Scid Gamma (NSG) mice, senescent cells were successfully eliminated when treated with the anti-uPAR CAR-T cells

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They dry the skin and can shift pH in ways that destabilize copper peptides

Protein concentrations were determined by the Bradford assay and equivalent amounts (1015 g) of total cellular proteins were separated by electrophoresis on a 12% SDS - polyacrylamide gel