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[Figure 3] Schematic diagram of endothelial cells that form the Blood-Brain Barrier and their associations with the perivascular end feet of astrocytes showing pathways across the BBB

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In many places, it exists in a regulatory gray area, being available for research purposes but not approved for human consumption

doi: 10.1002/smll.202410030 56 DawesG

Although EPO isn't suggested to treat any health condition, people claim the high levels of GLA are good for: Premenstrual syndrome (PMS) Eczema, atopic dermatitis, and other skin conditions Breast pain Menopausal relief (hot flashes) Dry eyes But many studies show no reason to suggest evening primrose oil helps these medical conditions