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Indeed, the success of Ozempic and its higher dose version, Wegovy has made its manufacturer, Novo Nordisk, headquartered in Denmark, Europe's most valuable company

Its steady

Reconstitute with bacteriostatic water before use and store dry at -20C

As a general clinical principle: Retest HbA1c no sooner than three months after commencing B12 replacement therapy, and ideally once haematological recovery has been confirmed Confirm haematological recovery normalisation of MCV and haemoglobin before interpreting the repeat HbA1c as reliable Use interim glucose monitoring such as fasting plasma glucose, OGTT, or self-monitored blood glucose (SMBG) to assess glycaemic control during the treatment period

Garcia-Fernandez M, Sierra I, Puche JE et al (2011) Liver mitochondrial dysfunction is reverted by insulin-like growth factor II (IGF-II) in aging rats