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It is capable of exerting activities of a putative cytoprotection mediator when native and stable in human gastric juice for more than 24 h [3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21,22,23,24,27,28,29,30,31,32,34,37,39,40] in contrast to conventional peptidergic growth factors

Cancer Res 1995;55:3964-8

"Determinants of Plasma Methylmalonic Acid in a Large Population: Implications for Assessment of Vitamin B12 Status." Clinical Chemistry, vol

It is non-acidic, caffeine-free, sugar-free, and non-carbonated

The main reason: the lack of randomized controlled clinical trials in humans

[16] The relationship to vitamin B12 deficiency has been the subject of many studies