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Various frameworks, such as MOF-derived oxygen-deficient titania, fluorinated TiO nanospindles, and coreshell TiO composites decorated with catalytic metals (MnO, Pt, Ru), are applied to enhance light or ultrasound responsiveness, improve ROS generation, and modulate the TME by depleting glutathione, decomposing HO, and alleviating hypoxia

In human and mouse IBD samples, ferroptosis-related genes are significantly upregulated, total ROS and lipid ROS levels are elevated in parallel, and the final product 4-hydroxynonenal(4-HNE) accumulates in large amounts [148]

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storage at ambient temperature in darkness is recommended Precautions & Notes Stability may be affected by light, heat, and extreme pH Experimental outcomes depend on concentration, model system, and formulation Appropriate controls are recommended for enzymatic and cellular assays Intended strictly for laboratory research use

Microglia are extremely mobile cells that quickly change their shape in order to exert their functions, and rearrangement of the cytoskeletal proteins, specifically actin microfilaments, is crucial in this process [87]

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