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Through conjugation with the DOTA chelator and subsequent radiolabeling with the positron-emitting radionuclide copper-64 ( 64 Cu), daratumumab has been successfully developed as a molecular probe targeting CD38-expressing MM cells [102]
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The benefits and risks must be considered in patients with recurrent infections, those who have a history of serious or opportunistic infection, or travel to areas of endemic mycoses, and in those who are immunosuppressed[106]
