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The blood catalase activity has been reported to be low in pregnant women with GDM compared to nonpregnant and pregnant nondiabetic healthy control women [72]

Here based on a matched comparative study, we showed that L-carnitine administration was unable to accelerate VPA clearance, speed blood lactate level normalization or limit organ dysfunction

Copper overload is a defining feature of Wilsons disease where mutations to the copper transporter ATP7B lead to impaired copper efflux and resultant accumulation in multiple organ systems including the CNS 39

2.9.5 Statistical analysis Every experiment was carried out in triplicate

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Indeed, the conversion of a catalytic Cys thiol into a disulfide is a powerful means for shutting down enzymatic activity because disulfides are poor nucleophiles compared to thiolates