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Hydroxocobalamin, the form most used in the UK, is released gradually, and a maintenance dose is often given every eight to twelve weeks

B12 plays a key role in red blood cell production, nerve function, and DNA synthesis

Briefly, after a 12-h fast, each subject swallowed a capsule containing 0.25 g of cyanocobalamin radio-labelled with 58 Co, followed immediately by an intramuscular injection of 1000 g of cyanocobalamin

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This creates a feedback loop in which quality control informs biogenesis, ensuring a constant renewal cycle essential for cardiac homeostasis