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These side effects often result from increased cell growth, tissue expansion, and shifts in metabolic processes, which are more pronounced with higher doses or prolonged use

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Primary pre-oligodendrocytes cultures were prepared from the forebrains of P2 Sprague Dawley (Charles River Laboratory) rat pups using a differential detachment method

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Konradi C, Yang CK, Zimmerman EI, Lohmann KM, Gresch P, Pantazopoulos H, et al