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The rat appears to be a better model than the rabbit for studying human CYP2E1 expression and its role in metabolism of xenobiotics (Wrighton and Stevens 1992

If acetylcysteine therapy is discontinued upon a toxicologists advice and liver function tests show improvement but have not yet returned to baseline or normal values, it is expected that liver function will normalize within two weeks

One individual per group was euthanized before addressing the next animal in each group to render differences arising from the time of day at euthanization (e.g., cecal mass changes resulting from differences in time post-food consumption) comparable across all groups

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Animals 9, 788

The skin brightening effect is cumulative over 812 weeks