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Disturbances in glutamate-mediated neurotransmission have been increasingly documented in a range of neuropsychiatric disorders including schizophrenia, substance abuse, mood disorders, Alzheimer's disease, and autism-spectrum disorders

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Molecules 29(1):136 Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hafeman DG, Hoekstra W (1973) Selenium: biochemical role as a component of glutathione peroxidase

79,80 In mammalian cells, the GATOR1 and GATOR2 complexes exhibit weak direct interactions and rely on the tetrameric KICSTOR complex and the KICSTOR-interacting VWCE protein to anchor GATOR1 to lysosomes under conditions of amino acid or glucose deprivation

In contrast, in Ayurvedic medicine and Western herbalism, turmeric serves primarily as an anti-inflammatory agent [57, 59]

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