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Previous studies demonstrated that different components in the p53/MDM2/ARF pathway, such as MDM2/MDM4 protein, negatively regulate the activity of p53 (6972)

IGF-1 LR3 in Stem Cell Self-Renewal Research Research has established that IGF-1 receptor signalling is necessary for human embryonic stem cell self-renewal, and that IGF-1 LR3 can substitute for native IGF-1 in stem cell cultures with increased potency and stability requiring lower concentrations for equivalent or superior biological effects compared to unmodified IGF-1

Both respiratory tract function and histopathological effects were seen when animals were exposed to acrolein at levels of 0.5 mg/m 3 or more for 90 days

10.1016/j.bpj.2013.01.051 18 ChenS.LiaoC.HuangH.WeissT.Bellisent-FunelM.SetteF

Blockade of airway inflammation by kaempferol via disturbing Tyk-STAT signaling in airway epithelial cells and in asthmatic mice

The chromatographic gradient was run at a flow rate of 0.150 mL/min as follows: 020 min.: linear gradient from 80% to 20% B